HitPredict

Interactor 1: IDD (P98153)
Integral membrane protein DGCR2/IDD
Gene: DGCR2

Interactor 2: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Lectin_C~Lectin_C
Common GO terms	GO:0030246 - carbohydrate binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 149
+	Hs
		688548 IDD_HUMAN (1-550): 7.15e-153: 450: 100.00		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		1022383 IDD_HUMAN (1-550): 7.15e-153: 450: 100.00		KLRD1_HUMAN (25-148): 9.98e-33: 115: 26.72
+	Hs
		1454332 TEN3_HUMAN (15-419): 8.1e-65: 231: 10.69		CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13
+	Hs
		1363117 SORL_HUMAN (108-407): 1.75e-38: 153: 10.53		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Hs
		158528 TENA_HUMAN (36-354): 2.26e-18: 91.5: 11.89		NCAN_HUMAN (8-146): 1.47e-45: 160: 19.21
+	Hs
		274906 LRP5_HUMAN (96-376): 6.2e-19: 93: 11.66		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Rn
		73580 B2LYI9_RAT (147-343): 8.25e-11: 67.2: 13.15		G3V8R2_RAT (8-146): 3.21e-46: 162: 20.53
+	Hs
		565114 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		CSPG2_HUMAN (8-146): 5.91e-44: 155: 21.85
+	Hs
		287597 LRP6_HUMAN (178-357): 3.8e-12: 71.4: 9.47		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Hs
		1363170 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00
+	Hs
		1449505 TEN2_HUMAN (248-419): 2.69e-15: 81.9: 14.52		CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13