HitPredict

Interactor 1: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0048786 - presynaptic active zone
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 1011
+	Hs
		259650 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		1202993 LIPB2_HUMAN (434-1149): 2.41e-95: 327: 18.61		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		1025318 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPB2_HUMAN (1-360): 1.13e-17: 90.7: 45.48
+	Hs
		259642 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA2_HUMAN (28-642): 1.06e-10: 68.1: 7.84
+	Hs
		255242 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA3_HUMAN (195-655): 3.13e-10: 66.5: 9.09
+	Hs
		1025277 LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Dm
		65319 A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21		A8DYM0_DROME (629-901): 1.14e-55: 212: 37.63
+	Hs
		259651 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPB2_HUMAN (1-360): 1.13e-17: 90.7: 45.48
+	Hs
		1146483 KAZRN_HUMAN (426-1152): 1.57e-78: 277: 20.33		KAZRN_HUMAN (179-892): 1.83e-62: 229: 19.28
+	Hs
		259634 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPA2_HUMAN (28-642): 1.06e-10: 68.1: 7.84
+	Hs
		255231 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		LIPA3_HUMAN (195-655): 3.13e-10: 66.5: 9.09
+	Dm
		1374287 Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95		Q9VU88_DROME (388-928): 2.17e-53: 200: 32.05
+	Dm
		65321 A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21		M9PCD4_DROME (56-568): 5.29e-11: 69.2: 7.13
+	Dm
		114427 Q9VU88_DROME (604-1148): 6.76e-85: 292: 22.95		M9PCD4_DROME (56-568): 5.29e-11: 69.2: 7.13
+	Hs
		522657 MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40		MYH4_HUMAN (185-793): 4.55e-19: 95.7: 9.05
+	Hs
		522585 MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40		MYH7_HUMAN (4-426): 2.63e-13: 76.8: 10.58
+	Hs
		502901 MYH6_HUMAN (1-705): 1.59e-30: 133: 11.65		MYH3_HUMAN (18-342): 1.75e-11: 70.7: 7.69