HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32476569, 35100065, 35914352
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 427
+	Hs
		1051276 DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83		IRF3_HUMAN (1-427): 0: 604: 100.00
+	Hs
		1056418 GRDN_HUMAN (135-355): 6.19e-09: 60.6: 21.34		IRF3_HUMAN (1-427): 0: 604: 100.00
+	Hs
		501006 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23
+	Hs
		536483 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		IRF2_HUMAN (1-116): 1.85e-48: 170: 33.90