Interactor 1: AIMP2 (Q13155)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)
Gene: AIMP2

Interactor 2: SYK (Q15046)
Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
Gene: KARS1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 25416956, 16189514, 28514442, 29997244, 32296183, 33961781, 22751010, 12819782, 26264872, 31792442, 9878398, 35235311, 21900206, 19584093, 21988832, 21536907, 24212136, 31116475, unassigned1304, 32814053
Identification Methods two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, cross-linking study, pull down, molecular sieving, amplified luminescent proximity homogeneous assay, x ray scattering, two hybrid prey pooling approach, two hybrid array and 5 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AIMP2_LysRS_bd~tRNA-synt_2, Thioredoxin_16~tRNA-synt_2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 320
Hs

1 597
+ Cg
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024