HitPredict

Interactor 1: CLH (P29742)
Clathrin heavy chain
Gene: Chc

Interactor 2: Q9W329 (Q9W329)
Golgi-localized, gamma-adaptin ear containing, ARF binding protein (Golgi-localizing gamma-ear-containing ARF-binding protein) (LD41311p)
Gene: Gga

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20067992
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Alpha_adaptinC2~Clathrin
Common GO terms	GO:0005802 - trans-Golgi network GO:0006886 - intracellular protein transport GO:0030136 - clathrin-coated vesicle GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1678 Dm			1 660
+	Hs
		1026272 CLH1_HUMAN (1-1660): 0: 2963: 80.17		GGA1_HUMAN (5-643): 4.71e-111: 350: 23.79
+	Hs
		1026255 CLH1_HUMAN (1-1660): 0: 2963: 80.17		GGA3_HUMAN (1-643): 7.06e-110: 349: 20.74
+	Hs
		1026271 CLH1_HUMAN (1-1660): 0: 2963: 80.17		GGA2_HUMAN (5-644): 5.35e-101: 322: 21.22
+	Hs
		1026101 CLH1_HUMAN (1-1660): 0: 2963: 80.17		TM1L2_HUMAN (5-495): 3.39e-93: 299: 14.62
+	Hs
		256463 CLH1_HUMAN (1-1660): 0: 2963: 80.17		TOM1_HUMAN (5-486): 3.75e-90: 290: 17.00
+	Mm
		1229285 CLH1_MOUSE (1-1660): 0: 2963: 80.23		HGS_MOUSE (1-642): 2.54e-74: 256: 11.11
+	Hs
		169514 CLH1_HUMAN (1-1660): 0: 2963: 80.17		HGS_HUMAN (1-642): 1.52e-73: 254: 10.52
+	Mm
		1229283 CLH1_MOUSE (1-1660): 0: 2963: 80.23		TM1L1_MOUSE (5-475): 1.67e-70: 238: 16.18
+	Hs
		1026158 CLH1_HUMAN (1-1660): 0: 2963: 80.17		STAM1_HUMAN (4-528): 5.05e-69: 236: 13.43
+	Hs
		290244 CLH1_HUMAN (1-1660): 0: 2963: 80.17		TM1L1_HUMAN (5-455): 3.11e-69: 235: 14.62
+	Hs
		225800 CLH1_HUMAN (1-1660): 0: 2963: 80.17		AP1G1_HUMAN (430-639): 2.21e-52: 195: 17.34
+	Dm
		715129 CLH_DROME (1-1678): 0: 2930: 100.00		HRS_DROME (6-620): 2.2e-62: 223: 11.49
+	Hs
		256456 CLH2_HUMAN (1-1634): 0: 2811: 77.11		TOM1_HUMAN (5-486): 3.75e-90: 290: 17.00
+	Hs
		169484 CLH2_HUMAN (1-1634): 0: 2811: 77.11		HGS_HUMAN (1-642): 1.52e-73: 254: 10.52
+	Hs
		922476 CLH2_HUMAN (1-1634): 0: 2811: 77.11		STAM1_HUMAN (4-528): 5.05e-69: 236: 13.43
+	Ce
		759666 CLH_CAEEL (5-1659): 0: 2767: 70.66		Q17796_CAEEL (5-378): 4.36e-63: 224: 12.72
+	Zm
		25451 A0A1D6IQ85_MAIZE (6-1638): 0: 2662: 56.65		C4J1G1_MAIZE (13-562): 3.41e-65: 227: 15.73
+	Sc
		644844 CLH_YEAST (5-1652): 0: 2442: 48.70		GGA1_YEAST (3-421): 4.5e-61: 215: 20.00
+	Sc
		644790 CLH_YEAST (5-1652): 0: 2442: 48.70		VPS27_YEAST (3-597): 1.52e-57: 207: 9.92
+	Sc
		644770 CLH_YEAST (5-1652): 0: 2442: 48.70		GGA2_YEAST (6-418): 1.2e-57: 206: 16.82