HitPredict

Interactor 1: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Interactor 2: THOC6 (Q86W42)
THO complex subunit 6 (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 825 Hs			1 341
+	Hs
		1027608 HNRPU_HUMAN (1-825): 0: 827: 100.00		POC1B_HUMAN (2-141): 3.52e-23: 101: 17.20
+	Hs
		1027602 HNRPU_HUMAN (1-825): 0: 827: 100.00		WDR36_HUMAN (18-259): 8.07e-18: 86.4: 17.00
+	Hs
		964855 HNRPU_HUMAN (1-825): 0: 827: 100.00		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		251009 HNRL2_HUMAN (6-730): 0: 550: 41.98		PRP17_HUMAN (1-284): 2.05e-47: 170: 9.33
+	Hs
		1380129 HNRL1_HUMAN (6-686): 0: 612: 45.76		FBXW7_HUMAN (1-149): 1.68e-20: 94.4: 7.38
+	Hs
		1387533 HNRL1_HUMAN (6-686): 0: 612: 45.76		SNR40_HUMAN (200-341): 7.62e-19: 88.2: 10.83
+	Hs
		1227374 HNRL1_HUMAN (6-686): 0: 612: 45.76		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Mm
		1297749 HNRL1_MOUSE (6-703): 0: 596: 45.00		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		1168861 HNRL2_HUMAN (6-730): 0: 550: 41.98		SNR40_HUMAN (200-341): 7.62e-19: 88.2: 10.83
+	Hs
		964988 HNRL2_HUMAN (6-730): 0: 550: 41.98		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		1363292 DDX1_HUMAN (257-619): 2.12e-84: 286: 21.41		FBXW7_HUMAN (1-149): 1.68e-20: 94.4: 7.38
+	Hs
		1227166 DDX1_HUMAN (257-619): 2.12e-84: 286: 21.41		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Mm
		1297762 DDX1_MOUSE (257-619): 3.14e-82: 280: 21.15		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Sc
		673598 MDN1_YEAST (36-296): 3.39e-34: 144: 16.73		NLE1_YEAST (1-283): 1.11e-60: 204: 14.67
+	Hs
		1227185 RYR2_HUMAN (176-667): 3.83e-61: 227: 14.34		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Hs
		641339 RYR1_HUMAN (176-536): 1.58e-53: 204: 12.85		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Hs
		1380227 ASH2L_HUMAN (157-486): 4.36e-49: 185: 19.29		FBXW7_HUMAN (1-149): 1.68e-20: 94.4: 7.38
+	Hs
		965302 ASH2L_HUMAN (157-486): 4.36e-49: 185: 19.29		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		1291948 ASH2L_HUMAN (157-486): 4.36e-49: 185: 19.29		WDR5B_HUMAN (1-102): 4.41e-14: 74: 14.82
+	Hs
		1220560 RN123_HUMAN (317-487): 2.69e-40: 163: 23.86		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39