HitPredict

Interactor 1: GRB10 (Q13322)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
Gene: GRB10

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 594 Hs			1 783
+	Hs
		1031700 GRB10_HUMAN (1-594): 0: 712: 100.00		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		1031710 GRB10_HUMAN (1-594): 0: 712: 100.00		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		1170525 RAPH1_HUMAN (34-484): 6.16e-107: 350: 23.94		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172216 VAV3_HUMAN (37-592): 1.1e-99: 323: 12.20		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		855804 VAV2_HUMAN (40-588): 1.7e-95: 313: 12.26		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1054043 GRB14_HUMAN (76-594): 0: 575: 55.08		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		1054101 GRB7_HUMAN (107-594): 1.36e-174: 507: 55.60		TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16
+	Hs
		433394 YES_HUMAN (441-592): 9.17e-47: 174: 20.89		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Dm
		112261 Q9VWB7_DROME (148-421): 4.57e-85: 289: 30.18		TRIM9_DROME (1-773): 1.9e-144: 443: 37.64
+	Hs
		536829 GRB14_HUMAN (76-594): 0: 575: 55.08		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		442893 HCK_HUMAN (406-593): 7.97e-46: 171: 18.78		TRIM1_HUMAN (107-779): 9.11e-128: 400: 23.32
+	Hs
		412294 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		412344 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		523126 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		FSD1_HUMAN (345-775): 1.45e-80: 268: 21.72
+	Hs
		433465 YES_HUMAN (441-592): 9.17e-47: 174: 20.89		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		523138 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		TRIM7_HUMAN (203-762): 1.89e-73: 249: 15.50
+	Hs
		412363 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		411977 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		442773 HCK_HUMAN (406-593): 7.97e-46: 171: 18.78		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		522983 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29