HitPredict

Interactor 1: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Interactor 2: FGF13 (Q92913)
Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)
Gene: FGF13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.685

Property	Details
Experiments	25814554, 12244047, 33961781, unassigned1126
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 245
+	Hs
		1032938 JIP2_HUMAN (1-824): 9.09e-151: 464: 100.00		FGF14_HUMAN (1-245): 3.86e-109: 316: 67.61
+	Hs
		899626 JIP2_HUMAN (1-824): 9.09e-151: 464: 100.00		FGF12_HUMAN (1-244): 1.77e-100: 293: 65.74
+	Hs
		1032937 JIP2_HUMAN (1-824): 9.09e-151: 464: 100.00		FGF11_HUMAN (3-223): 7.1e-96: 281: 58.04
+	Hs
		257680 ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77		FGF11_HUMAN (3-223): 7.1e-96: 281: 58.04
+	Hs
		257556 ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77		FGF3_HUMAN (52-227): 8.88e-53: 172: 29.17
+	Hs
		257591 ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77		FGF8_HUMAN (26-216): 1.63e-51: 169: 22.39
+	Hs
		1144634 TENS2_HUMAN (105-502): 5.26e-10: 65.4: 17.16		FGF21_HUMAN (36-230): 4.38e-46: 154: 22.02
+	Hs
		225913 ANR17_HUMAN (104-456): 4.22e-11: 69.1: 13.77		FGF17_HUMAN (53-206): 4.53e-39: 136: 21.66