HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: DAZP1 (Q96EP5)
DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)
Gene: DAZAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RanBP
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Hs			1 407
+	Hs
		341644 EYA4_HUMAN (3-271): 6.1e-39: 154: 18.02		DAZP1_HUMAN (1-407): 1.74e-75: 242: 100.00
+	Hs
		1102042 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		PABP4_HUMAN (4-196): 1.38e-34: 137: 19.49
+	Hs
		726754 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		TIA1_HUMAN (1-287): 1.12e-39: 147: 19.11
+	Hs
		550392 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		PABP1_HUMAN (3-201): 1.04e-31: 128: 18.91
+	Mm
		915302 EWS_MOUSE (1-656): 4.64e-42: 163: 94.06		TIA1_MOUSE (1-287): 1.18e-39: 147: 19.11
+	Hs
		909640 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		ROA3_HUMAN (80-200): 2.6e-28: 116: 30.08
+	Hs
		485303 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		650882 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		ROA2_HUMAN (103-200): 1.84e-25: 107: 32.65
+	Hs
		909535 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		ROA3_HUMAN (80-200): 2.6e-28: 116: 30.08
+	Hs
		485077 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		650706 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		ROA2_HUMAN (103-200): 1.84e-25: 107: 32.65
+	Sc
		403509 HRB1_YEAST (241-452): 4.77e-35: 140: 21.76		PABP_YEAST (2-197): 7.54e-35: 137: 20.71
+	Hs
		1032955 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		HNRPD_HUMAN (83-196): 2.14e-21: 96.4: 27.19
+	Hs
		775060 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		PABP4_HUMAN (4-196): 1.38e-34: 137: 19.49
+	Hs
		550147 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		PABP1_HUMAN (3-201): 1.04e-31: 128: 18.91
+	Hs
		774936 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		ROA3_HUMAN (80-200): 2.6e-28: 116: 30.08
+	Hs
		484962 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		ROA1_HUMAN (102-200): 1.27e-27: 114: 30.30
+	Hs
		650619 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		ROA2_HUMAN (103-200): 1.84e-25: 107: 32.65
+	Hs
		775076 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		HNRPD_HUMAN (83-196): 2.14e-21: 96.4: 27.19
+	Sc
		403371 GBP2_YEAST (343-453): 3.83e-16: 83.2: 24.56		PABP_YEAST (2-197): 7.54e-35: 137: 20.71