HitPredict

Interactor 1: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Interactor 2: RPN5 (Q12250)
26S proteasome regulatory subunit RPN5 (Proteasome non-ATPase subunit 5)
Gene: RPN5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 11805826, 14759368, 16554755, 16429126, 37968396, 31848235, 21289098
Identification Methods tandem affinity purification, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~PSMD12-CSN4_N, AAA_lid_3~PSMD12-CSN4_N
Common GO terms GO:0000502 - proteasome complex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 405
Sc

1 445
+ At
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Dm
+ Hs
+ Hs
+ At
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Sp
+ Dm
+ Sc

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Last updated: 11Aug2025