HitPredict

Interactor 1: SF3B2 (Q13435)
Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145)
Gene: SF3B2

Interactor 2: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PSP~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005689 - U12-type spliceosomal complex GO:0008380 - RNA splicing
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 895 Hs			1 217
+	Hs
		1034363 SF3B2_HUMAN (1-895): 0: 1129: 100.00		PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54
+	Hs
		1034292 SF3B2_HUMAN (1-895): 0: 1129: 100.00		SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84
+	Mm
		1112735 SF3B2_MOUSE (1-895): 0: 1082: 95.87		RBM4_MOUSE (11-103): 3.6e-19: 86.2: 22.58
+	Hs
		92678 E9PPJ0_HUMAN (1-895): 0: 1094: 98.10		SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84
+	Sc
		376903 CUS1_YEAST (326-754): 2.32e-111: 350: 26.77		PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60