HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1299
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (396-1295): 2.07e-31: 136: 9.60
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (718-1299): 7.56e-21: 102: 11.82
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (718-1299): 1.14e-20: 101: 10.10
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (719-1299): 3.77e-20: 99.8: 11.49
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (718-1299): 2.11e-19: 97.5: 11.47
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1035193 HDAC2_HUMAN (1-478): 0: 666: 85.92		ROCK1_HUMAN (649-1271): 9.18e-17: 88.6: 12.04
+	Hs
		1038397 HDAC1_HUMAN (1-482): 0: 668: 100.00		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		264367 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		GGYF1_HUMAN (1-619): 2.01e-71: 261: 46.64
+	Hs
		876528 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (705-1294): 1.67e-26: 120: 9.81
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (739-1030): 1.45e-09: 65: 16.72
+	Hs
		1068690 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		1354183 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MRCKB_HUMAN (731-1123): 2.65e-12: 73.9: 14.82
+	Hs
		1189812 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH14_HUMAN (719-1022): 6.74e-10: 66.2: 19.94