HitPredict

Interactor 1: FKBP4 (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FKBP_C~TPR_16, TPR_1~TPR_16, TPR_16~TPR_2
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 459 Hs			1 365
+	Hs
		1106143 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		76515 FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		916653 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Dm
		1478357 FKB59_DROME (20-450): 1.32e-129: 383: 42.92		Q9VJD4_DROME (9-226): 1.39e-47: 165: 17.73
+	Dm
		1475666 FKB59_DROME (20-450): 1.32e-129: 383: 42.92		Q9VH81_DROME (4-218): 1.06e-39: 149: 13.58
+	Hs
		185622 FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		1106073 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		185664 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		318008 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		TOM70_HUMAN (5-278): 4.48e-12: 69.1: 10.07
+	Dm
		1480500 FKB59_DROME (20-450): 1.32e-129: 383: 42.92		Q9VPN5_DROME (1-321): 9.81e-18: 86: 10.98
+	Hs
		124855 AIP_HUMAN (146-416): 2.83e-50: 175: 20.12		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1125745 FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		226714 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		SGTA_HUMAN (6-171): 3.2e-40: 146: 20.96
+	Hs
		731115 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		1125666 FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		185693 FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		731618 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		185913 FKB10_HUMAN (24-136): 2.16e-24: 108: 33.33		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		185466 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		1081544 Q0VDC6_HUMAN (149-248): 5.3e-23: 96.5: 25.00		TMTC1_HUMAN (21-137): 7.71e-16: 81.1: 17.36