HitPredict

Interactor 1: IQGA2 (Q13576)
Ras GTPase-activating-like protein IQGAP2
Gene: IQGAP2

Interactor 2: DRC8 (Q5VUJ9)
Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2)
Gene: EFCAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1575 Hs			1 269
+	Hs
		648499 IQGA2_HUMAN (1-1575): 0: 1336: 100.00		CALL3_HUMAN (144-268): 1.36e-44: 149: 32.00
+	Hs
		648473 IQGA1_HUMAN (9-1575): 0: 1223: 55.99		CALL3_HUMAN (144-268): 1.36e-44: 149: 32.00
+	Hs
		483913 IQGA1_HUMAN (9-1575): 0: 1223: 55.99		CALM1_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		483984 IQGA1_HUMAN (9-1575): 0: 1223: 55.99		CALM2_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		484079 IQGA1_HUMAN (9-1575): 0: 1223: 55.99		CALM3_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		57913 A2RRC9_HUMAN (18-1575): 0: 1216: 47.56		B4DJ51_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		483946 IQGA3_HUMAN (18-1575): 0: 1209: 47.63		CALM1_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		484020 IQGA3_HUMAN (18-1575): 0: 1209: 47.63		CALM2_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		484161 IQGA3_HUMAN (18-1575): 0: 1209: 47.63		CALM3_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		361210 IQGA1_HUMAN (9-1575): 0: 1223: 55.99		TNNC2_HUMAN (144-216): 6.91e-10: 58.6: 26.03
+	Sp
		144978 IQG1_SCHPO (4-1573): 0: 850: 23.00		CALM_SCHPO (142-268): 2.37e-46: 153: 30.71
+	Sc
		420355 IQG1_YEAST (37-1575): 0: 613: 16.60		CALM_YEAST (72-218): 8.78e-40: 137: 19.73
+	Hs
		484218 MYO5B_HUMAN (142-1456): 5.01e-105: 373: 11.77		CALM3_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		930560 MYO5A_HUMAN (230-1465): 4.4e-122: 425: 12.23		TNNC1_HUMAN (152-216): 8.61e-09: 55.5: 21.54
+	Hs
		930559 MYO5B_HUMAN (142-1456): 5.01e-105: 373: 11.77		TNNC1_HUMAN (152-216): 8.61e-09: 55.5: 21.54
+	Hs
		483957 SYGP1_HUMAN (880-1392): 1.06e-73: 273: 15.61		CALM1_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		851162 CNN1_HUMAN (12-286): 5.18e-76: 256: 15.81		TNNC1_HUMAN (152-216): 8.61e-09: 55.5: 21.54
+	Hs
		483950 ASPM_HUMAN (200-988): 9.05e-15: 82.4: 10.69		CALM1_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		484022 ASPM_HUMAN (200-988): 9.05e-15: 82.4: 10.69		CALM2_HUMAN (146-268): 1.59e-41: 141: 34.15
+	Hs
		484165 ASPM_HUMAN (200-988): 9.05e-15: 82.4: 10.69		CALM3_HUMAN (146-268): 1.59e-41: 141: 34.15