Protein: HOS3
Histone deacetylase HOS3 (EC 3.5.1.98)

Gene: HOS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: Q02959

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004407 - histone deacetylase activity
GO:0005628 - prospore membrane
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1040020

HOS3
Histone deacetylase HOS3

5

18

Small-scale

0.915

High

419849

H2A2
Histone H2A.2

3

16

High-throughput

0.817

High

963672

H3
Histone H3

3

20

Small-scale

0.817

High

381224

H2B1
Histone H2B.1

2

20

High-throughput

0.737

High

381606

H2B2
Histone H2B.2

2

20

High-throughput

0.737

High

850560

RSC8
Chromatin structure-remodeling complex protein RSC8

2

5

High-throughput

0.737

High

1040037

H2AZ
Histone H2A.Z

2

18

High-throughput

0.737

High

382298

H4
Histone H4

4

15

Small-scale

0.676

High

823025

ATAD2
ATPase histone chaperone YTA7

3

9

High-throughput

0.633

High

445368

CDC31
Cell division control protein 31

2

2

High-throughput

0.588

High

524935

HSP71
Heat shock protein SSA1

2

20

High-throughput

0.584

High

650010

SIN3
Transcriptional regulatory protein SIN3

1

20

High-throughput

0.575

High

917109

HOS2
Probable histone deacetylase HOS2

1

17

High-throughput

0.575

High

743125

STH1
Nuclear protein STH1/NPS1

2

20

High-throughput

0.571

High

744333

CHD1
Chromo domain-containing protein 1

2

20

High-throughput

0.571

High

794209

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

20

High-throughput

0.571

High

745607

RSC7
Chromatin structure-remodeling complex subunit RSC7

2

0

High-throughput

0.547

High

722202

XPO1
Exportin-1

1

10

High-throughput

0.536

High

1040035

WHI5
G1-specific transcriptional repressor WHI5

1

1

Small-scale

0.515

High

449001

TOP2
DNA topoisomerase 2

1

5

High-throughput

0.479

High

707980

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

739738

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.479

High

745853

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

8

High-throughput

0.479

High

763982

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

797252

HSL7
Protein arginine N-methyltransferase HSL7

1

3

Small-scale

0.479

High

801016

RFC1
Replication factor C subunit 1

1

2

High-throughput

0.479

High

893373

TAF4
Transcription initiation factor TFIID subunit 4

1

1

High-throughput

0.479

High

925005

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.479

High

1040030

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

1040032

SGO1
Shugoshin

1

1

High-throughput

0.479

High

1040034

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

813652

NUP60
Nucleoporin NUP60

1

0

Small-scale

0.458

High

1040038

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.458

High

393212

HSP82
ATP-dependent molecular chaperone HSP82

1

17

High-throughput

0.445

High

678337

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.445

High

694628

SPT5
Transcription elongation factor SPT5

1

3

High-throughput

0.445

High

736041

SP110
Spindle pole body component 110

1

20

High-throughput

0.445

High

736711

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

742247

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

781791

SET3
SET domain-containing protein 3

1

20

High-throughput

0.445

High

793979

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

20

High-throughput

0.445

High

804000

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

806346

KOG1
Target of rapamycin complex 1 subunit KOG1

1

19

High-throughput

0.445

High

807129

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

4

High-throughput

0.445

High

826168

SCC3
Cohesin subunit SCC3

1

1

High-throughput

0.445

High

865051

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.445

High

916591

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

3

High-throughput

0.445

High

1026810

CDC14
Tyrosine-protein phosphatase CDC14

1

5

High-throughput

0.445

High

1040022

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.445

High

1040023

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

5

High-throughput

0.445

High

1040024

RUVB1
RuvB-like protein 1

1

9

High-throughput

0.445

High

1040027

ARP9
Actin-like protein ARP9

1

8

High-throughput

0.445

High

1040029

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

1040036

RUVB2
RuvB-like protein 2

1

9

High-throughput

0.445

High

513557

RL1A
Large ribosomal subunit protein uL1A

1

6

High-throughput

0.437

High

795172

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

824776

MLP2
Protein MLP2

1

20

High-throughput

0.437

High

397498

REP1
Partitioning protein REP1

1

0

High-throughput

0.426

High

830228

RRN7
RNA polymerase I-specific transcription initiation factor RRN7

1

0

High-throughput

0.426

High

921161

H1
Histone H1

1

0

High-throughput

0.426

High

1040021

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

1040026

RRN11
RNA polymerase I-specific transcription initiation factor RRN11

1

0

High-throughput

0.426

High

1040031

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

817616

UTP7
U3 small nucleolar RNA-associated protein 7

1

20

High-throughput

0.407

High

864318

NET1
Nucleolar protein NET1

1

2

High-throughput

0.407

High

877975

NUP57
Nucleoporin NUP57

1

7

High-throughput

0.407

High

1035317

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.407

High

1040028

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.407

High

613784

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

1040033

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.249

Low

1040025

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025