Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35575683
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~EF-hand_7, Plectin~Plectin, SH3_10~Spectrin_3, CH~Spectrin, Spectrin~Spectrin_3, Spectrin_2~Spectrin_2, Spectrin_2~Spectrin_3, Spectrin_3~Spectrin_3
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030018 - Z disc
GO:0030056 - hemidesmosome
GO:0030424 - axon
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 7570
Hs

1 4684
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Ce
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025