HitPredict

Interactor 1: HMSH (Q03372)
Muscle segmentation homeobox (Protein drop) (Protein msh)
Gene: Dr

Interactor 2: NOC (Q24423)
Zinc finger protein Noc (Zinc finger protein NocA)
Gene: NOC

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007420 - brain development GO:0010629 - negative regulation of gene expression
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 515 Dm			1 537
+	Dm
		1014315 UBX_DROME (284-482): 7.29e-30: 122: 22.17		NOC_DROME (12-537): 1.44e-70: 237: 100.00
+	Hs
		772205 MSX2_HUMAN (347-496): 1.71e-33: 129: 53.29		ZN703_HUMAN (10-536): 5.77e-49: 180: 21.42
+	Hs
		942466 GSC_HUMAN (260-505): 3.2e-33: 128: 18.70		ZN703_HUMAN (10-536): 5.77e-49: 180: 21.42
+	Hs
		725320 TLX1_HUMAN (377-491): 1.57e-30: 123: 35.35		ZN703_HUMAN (10-536): 5.77e-49: 180: 21.42
+	Hs
		225113 TLX3_HUMAN (266-513): 7.66e-30: 120: 21.32		ZN703_HUMAN (10-536): 5.77e-49: 180: 21.42
+	Hs
		942450 GSC_HUMAN (260-505): 3.2e-33: 128: 18.70		KMT2C_HUMAN (21-537): 1.1e-42: 166: 11.68
+	Hs
		725285 TLX1_HUMAN (377-491): 1.57e-30: 123: 35.35		KMT2C_HUMAN (21-537): 1.1e-42: 166: 11.68
+	Hs
		225064 TLX3_HUMAN (266-513): 7.66e-30: 120: 21.32		KMT2C_HUMAN (21-537): 1.1e-42: 166: 11.68
+	Hs
		226574 TLX2_HUMAN (414-491): 5.28e-29: 117: 43.59		KMT2C_HUMAN (21-537): 1.1e-42: 166: 11.68
+	Hs
		942459 GSC_HUMAN (260-505): 3.2e-33: 128: 18.70		ZN503_HUMAN (10-536): 4.77e-39: 153: 19.90
+	Hs
		725302 TLX1_HUMAN (377-491): 1.57e-30: 123: 35.35		ZN503_HUMAN (10-536): 4.77e-39: 153: 19.90
+	Hs
		225078 TLX3_HUMAN (266-513): 7.66e-30: 120: 21.32		ZN503_HUMAN (10-536): 4.77e-39: 153: 19.90
+	Hs
		725330 TLX1_HUMAN (377-491): 1.57e-30: 123: 35.35		CHD7_HUMAN (153-511): 3.76e-12: 71.5: 12.37
+	Hs
		1453585 VSX1_HUMAN (271-493): 1.99e-29: 120: 20.00		CHD7_HUMAN (153-511): 3.76e-12: 71.5: 12.37
+	Hs
		225131 TLX3_HUMAN (266-513): 7.66e-30: 120: 21.32		CHD7_HUMAN (153-511): 3.76e-12: 71.5: 12.37
+	Hs
		214484 HXA2_HUMAN (308-491): 3.83e-31: 126: 23.68		SYNJ1_HUMAN (200-537): 1.09e-09: 63.4: 10.83
+	Hs
		226614 TLX2_HUMAN (414-491): 5.28e-29: 117: 43.59		CHD7_HUMAN (153-511): 3.76e-12: 71.5: 12.37