HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: CSTF1 (Q05048)
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)
Gene: CSTF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26030138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1493 Hs			1 431
+	Hs
		209251 ERCC6_HUMAN (1-1493): 0: 1167: 100.00		PRP4_HUMAN (305-429): 8.13e-15: 78.2: 20.47
+	Hs
		1410248 CHD8_HUMAN (177-1471): 0: 739: 16.90		TBL1Y_HUMAN (11-335): 2.42e-69: 230: 13.50
+	Hs
		965260 CHD8_HUMAN (177-1471): 0: 739: 16.90		WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75
+	Hs
		964955 CHD4_HUMAN (317-1426): 0: 725: 19.25		WDR5_HUMAN (2-289): 3.32e-58: 195: 17.75
+	Hs
		1088581 CHD3_HUMAN (317-1445): 0: 747: 19.86		NLE1_HUMAN (247-429): 1.32e-44: 163: 17.94
+	Hs
		1350646 CHD6_HUMAN (107-1487): 0: 804: 17.71		FBXW7_HUMAN (2-196): 1.01e-15: 81.4: 12.26
+	Dm
		674032 BRM_DROME (228-1361): 0: 668: 19.06		EBI_DROME (167-430): 5.68e-58: 203: 16.90
+	Hs
		1088500 CHD3_HUMAN (317-1445): 0: 747: 19.86		SNR40_HUMAN (3-195): 7.66e-29: 117: 19.50
+	Hs
		209257 CHD3_HUMAN (317-1445): 0: 747: 19.86		PRP4_HUMAN (305-429): 8.13e-15: 78.2: 20.47
+	Hs
		1088618 CHD3_HUMAN (317-1445): 0: 747: 19.86		PRP19_HUMAN (136-335): 3.91e-14: 76.3: 24.50
+	Hs
		1132879 CHD4_HUMAN (317-1426): 0: 725: 19.25		FBXW7_HUMAN (2-196): 1.01e-15: 81.4: 12.26
+	Hs
		209266 CHD4_HUMAN (317-1426): 0: 725: 19.25		PRP4_HUMAN (305-429): 8.13e-15: 78.2: 20.47
+	Hs
		1133048 CHD4_HUMAN (317-1426): 0: 725: 19.25		PRP19_HUMAN (136-335): 3.91e-14: 76.3: 24.50
+	Hs
		903453 SMCA4_HUMAN (228-1299): 0: 681: 20.36		SNR40_HUMAN (3-195): 7.66e-29: 117: 19.50
+	Hs
		703360 SMCA1_HUMAN (370-1322): 0: 665: 22.14		SNR40_HUMAN (3-195): 7.66e-29: 117: 19.50
+	Hs
		903450 SMCA4_HUMAN (228-1299): 0: 681: 20.36		FBXW7_HUMAN (2-196): 1.01e-15: 81.4: 12.26
+	Hs
		160123 CHD1_HUMAN (310-1492): 0: 630: 19.43		SNR40_HUMAN (3-195): 7.66e-29: 117: 19.50
+	Hs
		703359 SMCA1_HUMAN (370-1322): 0: 665: 22.14		FBXW7_HUMAN (2-196): 1.01e-15: 81.4: 12.26
+	Hs
		1387556 SMRCD_HUMAN (4-1008): 0: 628: 21.13		SNR40_HUMAN (3-195): 7.66e-29: 117: 19.50
+	Hs
		160120 CHD1_HUMAN (310-1492): 0: 630: 19.43		FBXW7_HUMAN (2-196): 1.01e-15: 81.4: 12.26