HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: TBX20 (Q9UMR3)
T-box transcription factor TBX20 (T-box protein 20)
Gene: TBX20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 447
+	Hs
		1047884 TLE1_HUMAN (1-772): 0: 553: 77.96		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		1048184 TLE4_HUMAN (1-772): 0: 541: 80.52		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		1048071 TLE3_HUMAN (1-772): 0: 597: 100.00		TBX15_HUMAN (11-429): 6.35e-127: 382: 38.98
+	Hs
		178494 TLE3_HUMAN (1-772): 0: 597: 100.00		TBX3_HUMAN (9-415): 2.98e-115: 356: 33.41
+	Hs
		181501 TLE3_HUMAN (1-772): 0: 597: 100.00		TBXT_HUMAN (81-415): 5.58e-110: 333: 34.81
+	Hs
		1047982 TLE3_HUMAN (1-772): 0: 597: 100.00		TBR1_HUMAN (7-380): 4.58e-105: 328: 31.25
+	Hs
		181500 TLE1_HUMAN (1-772): 0: 553: 77.96		TBXT_HUMAN (81-415): 5.58e-110: 333: 34.81
+	Hs
		1047830 TLE1_HUMAN (1-772): 0: 553: 77.96		TBR1_HUMAN (7-380): 4.58e-105: 328: 31.25
+	Hs
		216149 TLE1_HUMAN (1-772): 0: 553: 77.96		TBX1_HUMAN (75-379): 1.13e-107: 326: 43.00
+	Hs
		1206459 Q5JSZ1_HUMAN (1-202): 3.79e-114: 346: 72.69		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Hs
		181502 TLE4_HUMAN (1-772): 0: 541: 80.52		TBXT_HUMAN (81-415): 5.58e-110: 333: 34.81
+	Hs
		1048160 TLE4_HUMAN (1-772): 0: 541: 80.52		TBR1_HUMAN (7-380): 4.58e-105: 328: 31.25
+	Hs
		1212332 Q5T3G3_HUMAN (1-232): 5.32e-94: 294: 67.49		TBX20_HUMAN (1-447): 0: 530: 100.00
+	Dm
		594716 GROU_DROME (1-772): 1.44e-140: 433: 58.36		Q9VMR2_DROME (45-366): 4.1e-98: 307: 49.55
+	Hs
		178495 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		TBX3_HUMAN (9-415): 2.98e-115: 356: 33.41
+	Hs
		181504 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		TBXT_HUMAN (81-415): 5.58e-110: 333: 34.81
+	Hs
		1061713 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		TBR1_HUMAN (7-380): 4.58e-105: 328: 31.25
+	Hs
		351436 TLE5_HUMAN (1-200): 1.39e-100: 310: 62.19		TBX6_HUMAN (83-430): 6.74e-106: 322: 36.59
+	Ce
		146016 UNC37_CAEEL (18-686): 1.07e-81: 274: 17.53		TBX1_CAEEL (80-311): 3.44e-104: 311: 47.41
+	Ce
		146030 UNC37_CAEEL (18-686): 1.07e-81: 274: 17.53		TBX12_CAEEL (73-356): 5.98e-102: 309: 47.41