HitPredict

Interactor 1: SEPT6 (Q14141)
Septin-6
Gene: SEPTIN6

Interactor 2: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 25416956, 16189514, 28514442, 12388755, 33961781, 35271311, 26186194, 17803907, 17637674, 24633326, 31515488, 17229681
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Septin~Septin
Common GO terms GO:0000776 - kinetochore
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005819 - spindle
GO:0005940 - septin ring
and 12 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 434
Hs

1 361
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024