HitPredict

Interactor 1: SWA2 (Q06677)
Auxilin-like clathrin uncoating factor SWA2 (Bud site selection protein 24) (DnaJ-related protein SWA2) (J protein SWA2) (Synthetic lethal with ARF1 protein 2)
Gene: SWA2

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 668 Sc			1 700
+	Sc
		673677 SWA2_YEAST (1-668): 0: 554: 100.00		USO1_YEAST (2-469): 3.29e-16: 85.5: 11.39
+	Hs
		916729 PPP5_HUMAN (353-606): 3.75e-43: 164: 16.86		MRCKB_HUMAN (67-632): 2.5e-38: 155: 12.56
+	Hs
		776789 PPP5_HUMAN (353-606): 3.75e-43: 164: 16.86		MYH11_HUMAN (4-552): 9.83e-20: 96.9: 10.57
+	Hs
		773136 PPP5_HUMAN (353-606): 3.75e-43: 164: 16.86		MYH10_HUMAN (10-357): 1.7e-12: 73.2: 8.26
+	Hs
		269981 AUXI_HUMAN (500-664): 7.79e-42: 165: 23.98		MYH13_HUMAN (308-656): 1.62e-11: 70.1: 11.46
+	Hs
		773017 UN45A_HUMAN (358-656): 8.37e-42: 165: 15.33		MYH9_HUMAN (1-311): 9.55e-09: 61.2: 8.68
+	Hs
		772693 PPP5_HUMAN (353-606): 3.75e-43: 164: 16.86		MYH9_HUMAN (1-311): 9.55e-09: 61.2: 8.68
+	Dm
		1266782 Q9VH81_DROME (327-622): 1.92e-40: 157: 14.48		Q7K523_DROME (229-647): 1.92e-10: 66.5: 14.77
+	Hs
		157856 RPAP3_HUMAN (186-541): 1.13e-21: 101: 8.99		CTRO_HUMAN (149-643): 9.62e-11: 67.7: 14.74
+	Dm
		432226 Q9VHW4_DROME (370-556): 8.88e-20: 96.1: 18.72		MYSA_DROME (136-643): 7.2e-10: 64.6: 14.80
+	Hs
		731014 STIP1_HUMAN (364-644): 8.79e-17: 85.9: 13.88		MYH10_HUMAN (10-357): 1.7e-12: 73.2: 8.26