HitPredict

Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1992 Hs			1 726
+	Hs
		244437 TRIPC_HUMAN (1-1992): 0: 1579: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		131439 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		1350501 HECW2_HUMAN (924-1991): 0: 626: 14.87		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		1271460 HECW2_HUMAN (924-1991): 0: 626: 14.87		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Hs
		1199210 HECW2_HUMAN (924-1991): 0: 626: 14.87		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		131528 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		244809 NED4L_HUMAN (989-1990): 0: 588: 16.37		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		808106 NEDD4_HUMAN (814-1990): 2.08e-159: 528: 13.49		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Sc
		765374 RSP5_YEAST (1422-1990): 3.6e-164: 525: 19.59		GCN5_YEAST (284-417): 7.13e-37: 145: 31.88
+	At
		1275613 IMPA1_ARATH (347-905): 5.44e-164: 514: 14.61		GTE11_ARATH (1-266): 4.98e-32: 134: 17.23
+	At
		97804 IMPA2_ARATH (347-905): 3.96e-160: 504: 15.32		GTE11_ARATH (1-266): 4.98e-32: 134: 17.23
+	Hs
		131351 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244328 UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		983172 UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		999205 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		1199216 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		600256 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52
+	Hs
		998736 UBE3C_HUMAN (1697-1992): 3.54e-26: 119: 30.57		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		244616 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56