Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 33658012, 33824312
Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0006974 - DNA damage response
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1992
Hs

1 707
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Last updated: 15 Jul 2024