HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: FOXI1 (Q12951)
Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3)
Gene: FOXI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Hs			1 378
+	Hs
		1048154 TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59		FOXI1_HUMAN (1-378): 1.99e-102: 309: 100.00
+	Hs
		1047807 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXI1_HUMAN (1-378): 1.99e-102: 309: 100.00
+	Hs
		1047962 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXI1_HUMAN (1-378): 1.99e-102: 309: 100.00
+	Hs
		937721 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXA1_HUMAN (20-358): 5.24e-62: 207: 23.51
+	Hs
		937620 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXG1_HUMAN (121-363): 4.86e-59: 200: 32.13
+	Hs
		937722 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXA1_HUMAN (20-358): 5.24e-62: 207: 23.51
+	Hs
		1047886 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXA2_HUMAN (40-347): 5.37e-53: 184: 26.95
+	Mm
		1222115 TLE1_MOUSE (2-197): 2.16e-101: 310: 63.00		FOXG1_MOUSE (35-367): 1.41e-60: 204: 26.55
+	Hs
		1048176 TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		938010 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXA3_HUMAN (34-323): 4.33e-51: 175: 27.61
+	Hs
		1047857 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		1048155 TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Rn
		92868 D3ZCM7_RAT (2-197): 5.5e-99: 304: 63.00		FOXG1_RAT (35-367): 1.81e-60: 204: 26.55
+	Hs
		1047808 TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		1047961 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXC1_HUMAN (49-270): 9.78e-53: 185: 34.73
+	Hs
		938012 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXA3_HUMAN (34-323): 4.33e-51: 175: 27.61
+	Hs
		1048077 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		1047963 TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		1061681 TLE5_HUMAN (1-197): 3.11e-101: 292: 100.00		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		251391 TLE5_HUMAN (1-197): 3.11e-101: 292: 100.00		FOXD2_HUMAN (120-211): 8.6e-47: 168: 63.04