HitPredict

Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: FOXI1 (Q12951)
Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3)
Gene: FOXI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Hs			1 378
+	Hs
		1048154 TLE4_HUMAN (1-770): 0: 571: 86.53		FOXI1_HUMAN (1-378): 1.99e-102: 309: 100.00
+	Hs
		1047962 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXI1_HUMAN (1-378): 1.99e-102: 309: 100.00
+	Hs
		937721 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXA1_HUMAN (20-358): 5.24e-62: 207: 23.51
+	Hs
		937620 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXG1_HUMAN (121-363): 4.86e-59: 200: 32.13
+	Hs
		1047886 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXA2_HUMAN (40-347): 5.37e-53: 184: 26.95
+	Rn
		92868 D3ZCM7_RAT (1-770): 0: 576: 95.98		FOXG1_RAT (35-367): 1.81e-60: 204: 26.55
+	Mm
		1222115 TLE1_MOUSE (1-770): 0: 573: 96.76		FOXG1_MOUSE (35-367): 1.41e-60: 204: 26.55
+	Hs
		938010 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXA3_HUMAN (34-323): 4.33e-51: 175: 27.61
+	Hs
		1047857 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		1047808 TLE1_HUMAN (1-770): 0: 600: 100.00		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		1048176 TLE4_HUMAN (1-770): 0: 571: 86.53		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		937722 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXA1_HUMAN (20-358): 5.24e-62: 207: 23.51
+	Hs
		1048155 TLE4_HUMAN (1-770): 0: 571: 86.53		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		1047961 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXC1_HUMAN (49-270): 9.78e-53: 185: 34.73
+	Hs
		938012 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXA3_HUMAN (34-323): 4.33e-51: 175: 27.61
+	Hs
		1048077 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXB1_HUMAN (113-358): 2.56e-50: 173: 30.00
+	Hs
		1047963 TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29		FOXL1_HUMAN (73-309): 6.05e-49: 170: 36.15
+	Hs
		938011 TLE2_HUMAN (1-770): 5.33e-153: 465: 64.33		FOXA3_HUMAN (34-323): 4.33e-51: 175: 27.61
+	Dm
		594702 GROU_DROME (1-770): 3.06e-141: 434: 59.28		Q961V5_DROME (43-308): 2.49e-54: 183: 27.86
+	Dm
		594674 GROU_DROME (1-770): 3.06e-141: 434: 59.28		SLP1_DROME (43-308): 4.72e-54: 182: 28.21