HitPredict

Interactor 1: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	31586073, 26638075, 34079125, 35709258
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008017 - microtubule binding GO:0015631 - tubulin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1648 Hs			1 1140
+	Hs
		1066140 KIF14_HUMAN (1-1648): 0: 891: 100.00		EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43
+	Hs
		728480 KIF14_HUMAN (1-1648): 0: 891: 100.00		MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36
+	Hs
		725166 KIF14_HUMAN (1-1648): 0: 891: 100.00		MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95
+	Hs
		724838 KIF14_HUMAN (1-1648): 0: 891: 100.00		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		551712 KIF14_HUMAN (1-1648): 0: 891: 100.00		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		828586 KIF14_HUMAN (1-1648): 0: 891: 100.00		CENPF_HUMAN (101-707): 3.1e-10: 67: 13.08
+	Hs
		1101494 KIF7_HUMAN (353-1504): 1.73e-147: 490: 18.81		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1017538 KIF5A_HUMAN (352-1231): 5.44e-144: 472: 20.91		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		702916 KINH_HUMAN (356-1198): 1.07e-143: 470: 20.59		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1313774 KIFC3_HUMAN (34-705): 1.19e-161: 514: 25.83		TSG10_HUMAN (187-806): 2.38e-12: 73.2: 14.19
+	Hs
		725033 KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93