HitPredict

Interactor 1: CHD8 (Q09XV5)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Axis duplication inhibitor) (Duplin)
Gene: CHD8

Interactor 2: IMA5 (Q60960)
Importin subunit alpha-5 (Importin alpha-S1) (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta)
Gene: Kpna1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11744694
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2582 Mm			1 538
+	Mm
		204700 CHD8_MOUSE (1-2582): 0: 2398: 100.00		IMA4_MOUSE (1-538): 5e-144: 426: 45.66
+	Hs
		253698 CHD8_HUMAN (1-2582): 0: 2364: 95.67		IMA7_HUMAN (1-538): 8.11e-156: 457: 80.30
+	Mm
		911180 CHD8_MOUSE (1-2582): 0: 2398: 100.00		IMA1_MOUSE (1-538): 3.93e-142: 422: 44.69
+	Hs
		911389 CHD8_HUMAN (1-2582): 0: 2364: 95.67		IMA5_HUMAN (1-538): 3.54e-153: 450: 97.77
+	Hs
		179084 CHD8_HUMAN (1-2582): 0: 2364: 95.67		IMA6_HUMAN (1-538): 3.29e-147: 435: 79.37
+	Hs
		142624 CHD8_HUMAN (1-2582): 0: 2364: 95.67		IMA3_HUMAN (1-538): 6.1e-145: 429: 46.58
+	Hs
		911117 CHD8_HUMAN (1-2582): 0: 2364: 95.67		IMA1_HUMAN (1-538): 4.33e-144: 427: 44.51
+	Hs
		911225 CHD3_HUMAN (399-2065): 0: 988: 23.54		IMA5_HUMAN (1-538): 3.54e-153: 450: 97.77
+	Hs
		910870 CHD3_HUMAN (399-2065): 0: 988: 23.54		IMA1_HUMAN (1-538): 4.33e-144: 427: 44.51
+	Hs
		138674 CHD3_HUMAN (399-2065): 0: 988: 23.54		IMA4_HUMAN (1-538): 3.3e-143: 424: 45.66
+	Hs
		243579 SMCA5_HUMAN (701-1724): 0: 894: 26.67		IMA5_HUMAN (1-538): 3.54e-153: 450: 97.77
+	Hs
		703284 SMCA1_HUMAN (654-1707): 0: 890: 26.26		IMA5_HUMAN (1-538): 3.54e-153: 450: 97.77
+	Dm
		356826 CHDM_DROME (461-2065): 0: 891: 22.69		Q9V455_DROME (7-538): 1.92e-139: 414: 44.93
+	Hs
		253631 CHD4_HUMAN (422-1806): 0: 845: 24.77		IMA7_HUMAN (1-538): 8.11e-156: 457: 80.30
+	Hs
		911248 CHD4_HUMAN (422-1806): 0: 845: 24.77		IMA5_HUMAN (1-538): 3.54e-153: 450: 97.77
+	Hs
		179046 CHD4_HUMAN (422-1806): 0: 845: 24.77		IMA6_HUMAN (1-538): 3.29e-147: 435: 79.37
+	Hs
		142552 CHD4_HUMAN (422-1806): 0: 845: 24.77		IMA3_HUMAN (1-538): 6.1e-145: 429: 46.58
+	Hs
		910901 CHD4_HUMAN (422-1806): 0: 845: 24.77		IMA1_HUMAN (1-538): 4.33e-144: 427: 44.51
+	Dm
		1173935 ISWI_DROME (699-1743): 0: 847: 24.95		Q9V455_DROME (7-538): 1.92e-139: 414: 44.93
+	Dm
		911450 ISWI_DROME (699-1743): 0: 847: 24.95		IMA_DROME (3-538): 7.85e-121: 367: 43.41