HitPredict

Interactor 1: RPB1 (G3MZY8)
DNA-directed RNA polymerase II subunit RPB1 (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPAB5 (Q32P78)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L)
Gene: POLR2L

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	16769904
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003899 - DNA-directed RNA polymerase activity GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1970 Bt			1 67
+	Hs
		667257 RPB1_HUMAN (1-1611): 0: 1850: 100.00		RPAB5_HUMAN (1-67): 3.74e-35: 114: 100.00
+	Sp
		151893 RPB1_SCHPO (11-1678): 0: 1606: 54.06		RPAB5_SCHPO (1-67): 4.8e-33: 109: 71.64
+	Sc
		401888 RPB1_YEAST (11-1573): 0: 1585: 49.12		RPAB5_YEAST (1-67): 1.81e-30: 103: 72.06
+	Hs
		165033 RPC1_HUMAN (16-1487): 0: 1323: 32.82		RPAB5_HUMAN (1-67): 3.74e-35: 114: 100.00
+	Sc
		402191 RPC1_YEAST (11-1468): 0: 1319: 32.60		RPAB5_YEAST (1-67): 1.81e-30: 103: 72.06
+	Sc
		534216 RPA1_YEAST (11-1463): 0: 1096: 22.98		RPAB5_YEAST (1-67): 1.81e-30: 103: 72.06
+	Hv
		93870 D4GZX6_HALVD (12-946): 0: 1003: 36.51		D4GWX5_HALVD (1-62): 1e-23: 85.8: 41.27
+	At
		1320152 NRPD1_ARATH (12-1082): 0: 722: 21.19		NRPBA_ARATH (1-67): 7.02e-34: 111: 80.60
+	Hv
		93871 D4GZX7_HALVD (1053-1468): 8.96e-59: 211: 29.26		D4GWX5_HALVD (1-62): 1e-23: 85.8: 41.27
+	Hs
		339967 RPA1_HUMAN (960-1476): 4.26e-42: 172: 16.24		RPAB5_HUMAN (1-67): 3.74e-35: 114: 100.00
+	At
		1204054 NRPE1_ARATH (1009-1471): 4.5e-40: 166: 14.29		NRPBA_ARATH (1-67): 7.02e-34: 111: 80.60