HitPredict

Interactor 1: NEXN (Q0ZGT2)
Nexilin (F-actin-binding protein) (Nelin)
Gene: NEXN

Interactor 2: ANK3 (Q12955)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~I-set, Ank_2~I-set
Common GO terms	GO:0005886 - plasma membrane GO:0030018 - Z disc
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 675 Hs			1 4377
+	Hs
		541458 FGFR1_HUMAN (349-674): 3.55e-41: 162: 13.51		ANK3_HUMAN (1-4377): 0: 1969: 100.00
+	Hs
		541315 FGFR1_HUMAN (349-674): 3.55e-41: 162: 13.51		ANK1_HUMAN (1-683): 0: 712: 35.52
+	Hs
		592939 OBSCN_HUMAN (540-675): 1.13e-11: 70.9: 18.25		ANK1_HUMAN (1-683): 0: 712: 35.52
+	Hs
		592949 TITIN_HUMAN (73-672): 9.81e-09: 61: 11.09		ANK1_HUMAN (1-683): 0: 712: 35.52
+	Hs
		177188 MYOM1_HUMAN (255-675): 2.34e-13: 76.1: 10.83		ANR28_HUMAN (272-1147): 0: 675: 20.96
+	Hs
		177277 TITIN_HUMAN (73-672): 9.81e-09: 61: 11.09		ANR28_HUMAN (272-1147): 0: 675: 20.96
+	Hs
		541441 FGFR1_HUMAN (349-674): 3.55e-41: 162: 13.51		ANK2_HUMAN (1-749): 8.42e-153: 540: 33.77
+	Hs
		1030655 OBSCN_HUMAN (540-675): 1.13e-11: 70.9: 18.25		ANK2_HUMAN (1-749): 8.42e-153: 540: 33.77
+	Hs
		541734 FGFR1_HUMAN (349-674): 3.55e-41: 162: 13.51		ANFY1_HUMAN (331-1101): 4.74e-99: 352: 17.20