Interactor 1: TRXR1 (Q16881)
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)
Gene: TXNRD1
Interactor 2: TRXR2 (Q9NNW7)
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3)
Gene: TXNRD2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.62 | 1.00 | 0.789 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glutaredoxin~Pyr_redox_2, Pyr_redox_2~Pyr_redox_2, Pyr_redox_2~Pyr_redox_dim, Pyr_redox_dim~Pyr_redox_dim |
| Common GO terms | GO:0004362 - glutathione-disulfide reductase (NADPH) activity GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
