HitPredict

Interactor 1: RSP6 (Q18409)
Probable splicing factor, arginine/serine-rich 6 (CeSRp20) (RNA-binding protein srp-1)
Gene: rsp-6

Interactor 2: Q21155 (Q21155)
RRM domain-containing protein
Gene: rnp-5

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.723

Property	Details
Experiments	19123269
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 179 Ce			1 289
+	Hs
		853877 SRSF9_HUMAN (2-171): 6.45e-36: 126: 29.31		NCBP2_HUMAN (103-244): 5.98e-32: 117: 18.31
+	Hs
		1028553 SRSF9_HUMAN (2-171): 6.45e-36: 126: 29.31		RNPS1_HUMAN (4-242): 3.49e-26: 106: 26.95
+	Hs
		993014 SRSF1_HUMAN (2-170): 8.03e-31: 113: 31.84		RBM8A_HUMAN (71-211): 1.01e-31: 117: 17.73
+	Hs
		1028557 SRSF9_HUMAN (2-171): 6.45e-36: 126: 29.31		ELAV1_HUMAN (115-215): 3.16e-21: 93.4: 20.79
+	Hs
		992784 SRSF1_HUMAN (2-170): 8.03e-31: 113: 31.84		RNPS1_HUMAN (4-242): 3.49e-26: 106: 26.95
+	Hs
		853824 NCBP2_HUMAN (2-107): 6.1e-27: 101: 27.93		NCBP2_HUMAN (103-244): 5.98e-32: 117: 18.31
+	Hs
		1028546 SRSF9_HUMAN (2-171): 6.45e-36: 126: 29.31		RBM39_HUMAN (108-207): 1.22e-18: 87.4: 22.00
+	Hs
		516493 SRSF9_HUMAN (2-171): 6.45e-36: 126: 29.31		PABP1_HUMAN (113-223): 4.19e-18: 86.1: 22.52
+	Hs
		2069 A0A0B4J1Z1_HUMAN (2-112): 2.44e-28: 104: 48.65		RNPS1_HUMAN (4-242): 3.49e-26: 106: 26.95
+	Hs
		992743 SRSF1_HUMAN (2-170): 8.03e-31: 113: 31.84		ELAV2_HUMAN (120-212): 1.41e-21: 94.6: 21.51
+	At
		1163070 SR30_ARATH (2-174): 1.94e-31: 115: 26.23		CYP59_ARATH (57-223): 1.61e-19: 90.1: 18.34
+	At
		186862 SR34_ARATH (2-174): 5.04e-31: 115: 29.53		CYP59_ARATH (57-223): 1.61e-19: 90.1: 18.34
+	At
		1163069 Q9SPI1_ARATH (2-174): 2.11e-30: 114: 28.43		CYP59_ARATH (57-223): 1.61e-19: 90.1: 18.34
+	Hs
		992769 SRSF1_HUMAN (2-170): 8.03e-31: 113: 31.84		RBM39_HUMAN (108-207): 1.22e-18: 87.4: 22.00
+	Hs
		516478 SRSF1_HUMAN (2-170): 8.03e-31: 113: 31.84		PABP1_HUMAN (113-223): 4.19e-18: 86.1: 22.52
+	Mm
		936689 SRSF7_MOUSE (2-112): 9.09e-28: 106: 48.65		ELAV1_MOUSE (115-215): 3.6e-21: 93.1: 20.79
+	Mm
		936481 SRSF1_MOUSE (2-170): 8.03e-31: 113: 31.84		TIAR_MOUSE (127-219): 7e-17: 81.9: 19.63
+	Mm
		857340 SRSF1_MOUSE (2-170): 8.03e-31: 113: 31.84		TIA1_MOUSE (128-223): 2.56e-16: 79.9: 27.08
+	Hs
		853881 NCBP2_HUMAN (2-107): 6.1e-27: 101: 27.93		PABP4_HUMAN (113-223): 3.61e-19: 89.2: 22.52
+	Hs
		516425 NCBP2_HUMAN (2-107): 6.1e-27: 101: 27.93		PABP1_HUMAN (113-223): 4.19e-18: 86.1: 22.52