HitPredict

Interactor 1: Q19818 (Q19818)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: nhl-2

Interactor 2: Q27GU1 (Q27GU1)
Piwi domain-containing protein
Gene: csr-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30575518
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043186 - P granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1032 Ce			1 867
+	Hs
		585070 RO52_HUMAN (144-624): 1.88e-104: 337: 11.70		AGO3_HUMAN (2-863): 0: 844: 18.23
+	Hs
		170478 TIF1A_HUMAN (36-754): 1.02e-94: 326: 14.50		AGO3_HUMAN (2-863): 0: 844: 18.23
+	Hs
		170510 TIF1A_HUMAN (36-754): 1.02e-94: 326: 14.50		AGO1_HUMAN (1-863): 0: 842: 17.47
+	Hs
		585074 RO52_HUMAN (144-624): 1.88e-104: 337: 11.70		AGO4_HUMAN (1-862): 0: 827: 17.72
+	Hs
		170508 TIF1A_HUMAN (36-754): 1.02e-94: 326: 14.50		AGO2_HUMAN (2-847): 0: 835: 17.81
+	Ce
		998324 Q19818_CAEEL (1-1032): 0: 756: 100.00		YQ53_CAEEL (258-836): 5.62e-123: 398: 20.52
+	Hs
		170484 TIF1A_HUMAN (36-754): 1.02e-94: 326: 14.50		AGO4_HUMAN (1-862): 0: 827: 17.72
+	Dm
		1103819 BRAT_DROME (654-1015): 5.31e-88: 307: 23.98		Q32KD4_DROME (1-852): 0: 823: 17.37
+	Hs
		1290902 TRI11_HUMAN (150-608): 5.89e-87: 289: 10.40		AGO2_HUMAN (2-847): 0: 835: 17.81
+	Dm
		1100037 BRAT_DROME (654-1015): 5.31e-88: 307: 23.98		Q27IR0_DROME (1-828): 0: 799: 17.55
+	Hs
		164503 TRI66_HUMAN (47-644): 1.37e-70: 259: 16.37		AGO2_HUMAN (2-847): 0: 835: 17.81
+	Dm
		1103862 Q9W378_DROME (13-450): 1.45e-66: 246: 21.59		Q32KD4_DROME (1-852): 0: 823: 17.37
+	Mm
		1208468 TRI32_MOUSE (121-829): 6.74e-57: 210: 14.03		AGO1_MOUSE (1-863): 0: 842: 17.47
+	Dm
		1100039 Q9W378_DROME (13-450): 1.45e-66: 246: 21.59		Q27IR0_DROME (1-828): 0: 799: 17.55
+	Ce
		108593 LIN41_CAEEL (88-960): 2.49e-63: 236: 11.55		G5EGR6_CAEEL (9-851): 0: 793: 17.20
+	Hs
		1102507 LIN41_HUMAN (631-1008): 8.18e-35: 145: 15.40		AGO2_HUMAN (2-847): 0: 835: 17.81
+	Dm
		1103832 WECH_DROME (836-1008): 1.15e-33: 141: 18.82		Q32KD4_DROME (1-852): 0: 823: 17.37
+	Dm
		1100038 WECH_DROME (836-1008): 1.15e-33: 141: 18.82		Q27IR0_DROME (1-828): 0: 799: 17.55
+	Ce
		1094449 LIN41_CAEEL (88-960): 2.49e-63: 236: 11.55		WAGO1_CAEEL (2-866): 0: 561: 20.54
+	Ce
		712395 NCL1_CAEEL (86-917): 2e-48: 188: 14.50		NRDE3_CAEEL (8-864): 3.72e-159: 494: 18.30