Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: APC5 (Q9UJX4)
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)
Gene: ANAPC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.734

The method score is based on:

Property Details
Experiments 26496610, 28514442, 35271311, 33961781, 20360068, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 6 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 620
Hs

1 755
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Sc
+ Sc
+ At
+ Xl
+ At
+ At

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Last updated: 11Aug2025