Interactor 1: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23
Interactor 2: APC5 (Q9UJX4)
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)
Gene: ANAPC5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.922 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 35271311, 33961781, 20360068, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ANAPC8~Apc5_N, ANAPC5~TPR_11, ANAPC5~TPR_8, Apc5_N~TPR_8 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005680 - anaphase-promoting complex GO:0005829 - cytosol GO:0007346 - regulation of mitotic cell cycle GO:0031145 - anaphase-promoting complex-dependent catabolic process and 6 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Xl | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
