Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: APC5 (Q9UJX4)
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)
Gene: ANAPC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 15082755, 33961781, 12956947, 20686030, 25306918, 26811472, 27114510, 32152539, 32076268, 10922056, 35271311, 35952650, 14657031, 22193957, 16364912, 22792066, 21043528, 21241890, 20360068, unassigned3799
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC5~TPR_8, Apc5_N~TPR_8
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005819 - spindle
GO:0005829 - cytosol
and 8 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 824
Hs

1 755
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs
+ Sp
+ Sc
+ Sc
+ At
+ At

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Last updated: 11Aug2025