Interactor 1: APC7 (Q9UJX3)
Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)
Gene: ANAPC7

Interactor 2: APC5 (Q9UJX4)
Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)
Gene: ANAPC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 33961781, 23160376, 20360068, 34819669, unassigned3799
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC5~TPR_8, Apc5_N~TPR_8
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005819 - spindle
GO:0005829 - cytosol
and 9 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 565
Hs

1 755
+ Hs
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+ Sp
+ Sc
+ Sc
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+ Xl
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+ At

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Last updated: 11Aug2025