HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: RASF1 (Q9NS23)
Ras association domain-containing protein 1
Gene: RASSF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 26186194, 24366813, 28514442, 28205554, 33961781, 17598981, 26578655, 24981860, 35271311, 36736316, 20562859, 24255178, 23455922, 14729613, 23386615, 20920251, 15109305
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mst1_SARAH~Nore1-SARAH, C1_1~Pkinase, Nore1-SARAH~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0050821 - protein stabilization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 11Aug2025