HitPredict

Interactor 1: CAF1A (Q13111)
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)
Gene: CHAF1A

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	21724829, 23075851
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CAF1-p150_C2~Histone, CAF1A~Histone
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 136
+	Hs
		998268 CAF1A_HUMAN (1-956): 0: 589: 100.00		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		1016817 CAF1A_HUMAN (1-956): 0: 589: 100.00		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		1094683 CAF1A_HUMAN (1-956): 0: 589: 100.00		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Hs
		883526 CAF1A_HUMAN (1-956): 0: 589: 100.00		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Mm
		1016772 CAF1A_MOUSE (1-933): 1.43e-158: 491: 60.47		H32_MOUSE (1-136): 6.24e-61: 185: 100.00
+	Hs
		998438 NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		1016949 NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		883582 NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Mm
		381754 TAOK2_MOUSE (171-716): 2.78e-37: 154: 12.88		H3C_MOUSE (1-136): 1.49e-61: 186: 95.59
+	Sc
		751675 SEC3_YEAST (32-630): 3.07e-36: 151: 13.11		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Hs
		270798 ROCK2_HUMAN (143-739): 2.86e-24: 112: 10.98		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		998920 BAZ2B_HUMAN (290-558): 5.73e-23: 108: 17.80		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Sc
		751660 SEC3_YEAST (32-630): 3.07e-36: 151: 13.11		CENPA_YEAST (18-134): 2.58e-43: 143: 56.67
+	Sp
		489136 CAF1A_SCHPO (263-604): 3.14e-23: 107: 22.04		H31_SCHPO (1-136): 3.44e-59: 181: 91.91
+	Sc
		963813 CAF1A_YEAST (262-645): 1.06e-24: 112: 21.47		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Hs
		998464 WDR87_HUMAN (49-725): 1.78e-12: 74.1: 11.35		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Sc
		779389 CAF1A_YEAST (262-645): 1.06e-24: 112: 21.47		CENPA_YEAST (18-134): 2.58e-43: 143: 56.67
+	Dm
		87264 Q9W3D1_DROME (112-670): 3.8e-10: 66.4: 8.39		H33A_DROME (1-136): 2.57e-61: 186: 97.06
+	Dm
		381748 Q9W3D1_DROME (112-670): 3.8e-10: 66.4: 8.39		H3_DROME (1-136): 6.24e-61: 185: 100.00