HitPredict

Interactor 1: HEP (Q23977)
Dual specificity mitogen-activated protein kinase kinase hemipterous (MAPKK) (EC 2.7.12.2)
Gene: HEP

Interactor 2: JIP1 (Q9W0K0)
JNK-interacting protein 1 (JIP-1) (APP-like-interacting protein 1) (APLIP1) (Protein eye developmental SP512)
Gene: Aplip1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 11912189, 17658258
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005078 - MAP-kinase scaffold activity
GO:0007254 - JNK cascade
GO:0019901 - protein kinase binding
GO:0030424 - axon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1178
Dm

1 490
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024