HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: ING3 (Q9NXR8)
Inhibitor of growth protein 3 (p47ING3)
Gene: ING3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 418
+	Hs
		397075 ESR1_HUMAN (10-432): 3.47e-112: 345: 21.37		ING3_HUMAN (1-418): 1.65e-142: 414: 100.00
+	Hs
		1095516 NR1H3_HUMAN (12-373): 3.97e-102: 314: 25.89		ING3_HUMAN (1-418): 1.65e-142: 414: 100.00
+	Mm
		1222881 ERR2_MOUSE (9-375): 1.51e-99: 307: 27.37		ING3_MOUSE (1-418): 7.84e-145: 420: 94.06
+	Hs
		933960 NR1H2_HUMAN (9-373): 1.55e-97: 303: 22.09		ING3_HUMAN (1-418): 1.65e-142: 414: 100.00
+	Hs
		834085 HNF4A_HUMAN (1-474): 0: 542: 100.00		ING1_HUMAN (33-162): 1.97e-30: 123: 16.30
+	Hs
		833965 HNF4A_HUMAN (1-474): 0: 542: 100.00		TAF3_HUMAN (324-407): 1.1e-17: 87.4: 24.72
+	Hs
		834073 HNF4A_HUMAN (1-474): 0: 542: 100.00		CXXC1_HUMAN (340-418): 1.04e-17: 87.4: 28.24
+	Hs
		396837 ESR1_HUMAN (10-432): 3.47e-112: 345: 21.37		DIDO1_HUMAN (110-410): 3.67e-40: 155: 14.74
+	Mm
		650048 RARB_MOUSE (13-424): 4.7e-108: 330: 25.18		ING4_MOUSE (2-181): 3.76e-44: 155: 23.81
+	Hs
		397179 ESR1_HUMAN (10-432): 3.47e-112: 345: 21.37		ING1_HUMAN (33-162): 1.97e-30: 123: 16.30