HitPredict

Interactor 1: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30126976
Identification Methods	p8 filamentous phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1484 Hs			1 1655
+	Hs
		1006059 NMDE2_HUMAN (1-1484): 0: 1859: 100.00		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Rn
		723877 NMDE2_RAT (1-1484): 0: 1842: 98.45		DLG4_RAT (812-1187): 5.61e-49: 189: 22.42
+	Mm
		1029202 NMDE2_MOUSE (1-1484): 0: 1838: 98.45		DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42
+	Hs
		1098529 NMDE2_HUMAN (1-1484): 0: 1859: 100.00		DLG3_HUMAN (724-947): 1.79e-19: 97.4: 31.23
+	Rn
		1028064 NMDE2_RAT (1-1484): 0: 1842: 98.45		DLG1_RAT (955-1182): 3.1e-24: 112: 37.56
+	Hs
		1098522 NMDE2_HUMAN (1-1484): 0: 1859: 100.00		DLG2_HUMAN (591-851): 2.07e-16: 87.5: 16.79
+	Rn
		1028067 NMDE2_RAT (1-1484): 0: 1842: 98.45		DLG2_RAT (816-1021): 6.73e-21: 101: 22.33
+	Hs
		1091487 NMDE2_HUMAN (1-1484): 0: 1859: 100.00		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Rn
		1028065 NMDE2_RAT (1-1484): 0: 1842: 98.45		DLG3_RAT (724-947): 3.66e-19: 96.3: 31.23
+	Mm
		1029241 NMDE2_MOUSE (1-1484): 0: 1838: 98.45		DLG2_MOUSE (567-848): 1.73e-20: 100: 16.89
+	Mm
		999782 NMDE2_MOUSE (1-1484): 0: 1838: 98.45		DLG3_MOUSE (724-947): 3.66e-19: 96.3: 31.23
+	Hs
		1098533 NMDE2_HUMAN (1-1484): 0: 1859: 100.00		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Mm
		1029222 NMDE2_MOUSE (1-1484): 0: 1838: 98.45		DLG1_MOUSE (688-910): 1.27e-14: 81.7: 23.91
+	Rn
		1000482 NMDE2_RAT (1-1484): 0: 1842: 98.45		LRRC7_RAT (816-951): 7.41e-09: 63.2: 27.54
+	Mm
		1029218 NMDE2_MOUSE (1-1484): 0: 1838: 98.45		LRRC7_MOUSE (816-951): 7.93e-09: 62.8: 27.54
+	Mm
		771423 NMDE1_MOUSE (9-1484): 0: 1524: 52.79		DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42
+	Rn
		723876 NMDE1_RAT (9-1484): 0: 1515: 52.59		DLG4_RAT (812-1187): 5.61e-49: 189: 22.42
+	Rn
		1028055 NMDE1_RAT (9-1484): 0: 1515: 52.59		DLG1_RAT (955-1182): 3.1e-24: 112: 37.56
+	Rn
		1028057 NMDE1_RAT (9-1484): 0: 1515: 52.59		DLG2_RAT (816-1021): 6.73e-21: 101: 22.33
+	Rn
		1028056 NMDE1_RAT (9-1484): 0: 1515: 52.59		DLG3_RAT (724-947): 3.66e-19: 96.3: 31.23