HitPredict

Interactor 1: SP140 (Q13342)
Nuclear body protein SP140 (Lymphoid-restricted homolog of Sp100) (LYSp100) (Nuclear autoantigen Sp-140) (Speckled 140 kDa)
Gene: SP140

Interactor 2: ZMY11 (Q15326)
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Gene: ZMYND11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	35044719
Identification Methods	phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain, Bromodomain~PHD
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 867 Hs			1 602
+	Hs
		1146252 CBP_HUMAN (136-859): 1.33e-61: 230: 10.03		ZMY11_HUMAN (1-602): 0: 608: 100.00
+	Hs
		659318 SP100_HUMAN (10-692): 4.51e-93: 314: 32.79		TRI33_HUMAN (57-304): 6.51e-41: 161: 16.67
+	Hs
		1460364 BAZ2A_HUMAN (134-864): 7.88e-76: 272: 12.95		TRI33_HUMAN (57-304): 6.51e-41: 161: 16.67
+	Mm
		107090 F8VPR5_MOUSE (136-859): 5.47e-65: 240: 9.49		TRI33_MOUSE (48-291): 3.19e-41: 162: 16.55
+	Hs
		180887 CBP_HUMAN (136-859): 1.33e-61: 230: 10.03		TIF1A_HUMAN (90-301): 1.3e-44: 172: 20.25
+	Hs
		180961 TRI33_HUMAN (284-861): 9.77e-59: 220: 14.96		TIF1A_HUMAN (90-301): 1.3e-44: 172: 20.25
+	Mm
		1225316 TRI33_MOUSE (284-861): 7.51e-56: 211: 14.80		TIF1A_MOUSE (90-301): 4.45e-44: 170: 18.99
+	Hs
		1462500 TRI33_HUMAN (284-861): 9.77e-59: 220: 14.96		TRI33_HUMAN (57-304): 6.51e-41: 161: 16.67
+	Mm
		107094 F8VPR5_MOUSE (136-859): 5.47e-65: 240: 9.49		KAT2B_MOUSE (122-254): 1.25e-31: 132: 18.52
+	Hs
		1368446 CBP_HUMAN (136-859): 1.33e-61: 230: 10.03		KAT2B_HUMAN (122-254): 2.58e-31: 131: 17.78
+	Hs
		1100185 CBP_HUMAN (136-859): 1.33e-61: 230: 10.03		TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29
+	Hs
		1100545 TRI33_HUMAN (284-861): 9.77e-59: 220: 14.96		TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29
+	Hs
		1067567 EP300_HUMAN (151-859): 3.12e-56: 213: 10.56		KAT2B_HUMAN (122-254): 2.58e-31: 131: 17.78
+	Hs
		1067267 EP300_HUMAN (151-859): 3.12e-56: 213: 10.56		TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29
+	Hs
		639825 SP110_HUMAN (40-475): 3.21e-57: 210: 19.60		TAF1_HUMAN (129-459): 8.78e-25: 112: 12.20
+	Mm
		107095 F8VPR5_MOUSE (136-859): 5.47e-65: 240: 9.49		KAT2A_MOUSE (146-254): 7.82e-14: 76.8: 22.02
+	Hs
		1429937 SP110_HUMAN (40-475): 3.21e-57: 210: 19.60		BRD8_HUMAN (115-273): 7.4e-23: 105: 15.72
+	Hs
		1288013 TRI33_HUMAN (284-861): 9.77e-59: 220: 14.96		PB1_HUMAN (161-507): 5.85e-19: 93.6: 12.81
+	Hs
		1086837 TRI33_HUMAN (284-861): 9.77e-59: 220: 14.96		BPTF_HUMAN (85-557): 3.26e-16: 85.1: 13.15