HitPredict

Interactor 1: ADA15 (Q13444)
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)
Gene: ADAM15

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	18296648
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 863 Hs			1 451
+	Hs
		557284 ADA15_HUMAN (1-863): 0: 559: 100.00		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		440542 ADA15_HUMAN (1-863): 0: 559: 100.00		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		463083 ADA15_HUMAN (1-863): 0: 559: 100.00		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		440062 ADA15_HUMAN (1-863): 0: 559: 100.00		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		473413 ADA15_HUMAN (1-863): 0: 559: 100.00		HCK_HUMAN (4-449): 7.51e-179: 511: 39.82
+	Hs
		362279 ADA15_HUMAN (1-863): 0: 559: 100.00		ABL1_HUMAN (1-449): 1.85e-170: 510: 35.17
+	Hs
		463505 ADA15_HUMAN (1-863): 0: 559: 100.00		LYN_HUMAN (3-449): 6.74e-177: 506: 38.19
+	Hs
		209872 ADA12_HUMAN (42-856): 4.89e-170: 518: 35.70		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		209868 ADA12_HUMAN (42-856): 4.89e-170: 518: 35.70		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		557462 ADA19_HUMAN (8-859): 3.65e-169: 517: 32.78		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		209870 ADA12_HUMAN (42-856): 4.89e-170: 518: 35.70		HCK_HUMAN (4-449): 7.51e-179: 511: 39.82
+	Hs
		473471 ADA19_HUMAN (8-859): 3.65e-169: 517: 32.78		HCK_HUMAN (4-449): 7.51e-179: 511: 39.82
+	Hs
		463504 ADAM9_HUMAN (31-815): 5.19e-172: 520: 31.31		LYN_HUMAN (3-449): 6.74e-177: 506: 38.19
+	Hs
		209869 ADA12_HUMAN (42-856): 4.89e-170: 518: 35.70		LYN_HUMAN (3-449): 6.74e-177: 506: 38.19
+	Hs
		557217 ADAM8_HUMAN (1-851): 1.37e-165: 503: 31.19		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		463755 ADA19_HUMAN (8-859): 3.65e-169: 517: 32.78		LYN_HUMAN (3-449): 6.74e-177: 506: 38.19
+	Hs
		1065080 ADA15_HUMAN (1-863): 0: 559: 100.00		ITK_HUMAN (7-447): 5.63e-153: 449: 32.60
+	Hs
		473479 ADA22_HUMAN (7-842): 8.99e-144: 449: 25.08		HCK_HUMAN (4-449): 7.51e-179: 511: 39.82
+	Hs
		463807 ADA22_HUMAN (7-842): 8.99e-144: 449: 25.08		LYN_HUMAN (3-449): 6.74e-177: 506: 38.19
+	Hs
		160962 ADA10_HUMAN (69-525): 4.12e-92: 308: 23.11		ABL1_HUMAN (1-449): 1.85e-170: 510: 35.17