Interactor 1: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Interactor 2: AXIN2 (Q9Y2T1)
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Gene: AXIN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.46 0.60 0.529

The method score is based on:

Property Details
Experiments 35512704
Identification Methods anti tag coimmunoprecipitation, split luciferase complementation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001649 - osteoblast differentiation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 552
Hs

1 843
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025