HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: EFNB3 (Q15768)
Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8)
Gene: EFNB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 340
+	Hs
		1153466 TBB8_HUMAN (1-427): 0: 705: 87.59		EFNB3_HUMAN (1-340): 8.45e-134: 386: 100.00
+	Hs
		457463 TBB5_HUMAN (1-429): 0: 704: 93.94		EFNB3_HUMAN (1-340): 8.45e-134: 386: 100.00
+	Hs
		997356 TBB4B_HUMAN (1-427): 0: 703: 93.91		EFNB3_HUMAN (1-340): 8.45e-134: 386: 100.00
+	Hs
		457228 TBB5_HUMAN (1-429): 0: 704: 93.94		EFNA1_HUMAN (18-200): 6.85e-71: 221: 24.87
+	Hs
		914197 TBB3_HUMAN (1-450): 0: 723: 100.00		EFNA3_HUMAN (29-239): 2.97e-63: 202: 25.34
+	Hs
		635282 TBB6_HUMAN (1-446): 0: 700: 92.38		EFNA1_HUMAN (18-200): 6.85e-71: 221: 24.87
+	Hs
		457324 TBB5_HUMAN (1-429): 0: 704: 93.94		EFNA3_HUMAN (29-239): 2.97e-63: 202: 25.34
+	Hs
		914189 TBB4B_HUMAN (1-427): 0: 703: 93.91		EFNA3_HUMAN (29-239): 2.97e-63: 202: 25.34
+	Hs
		914214 TBB2B_HUMAN (1-430): 0: 703: 93.72		EFNA3_HUMAN (29-239): 2.97e-63: 202: 25.34
+	Hs
		231306 TBB3_HUMAN (1-450): 0: 723: 100.00		EFNA2_HUMAN (29-163): 8.77e-51: 169: 31.47
+	Hs
		914254 TBB3_HUMAN (1-450): 0: 723: 100.00		EFNA4_HUMAN (30-175): 5.99e-49: 164: 27.21
+	Hs
		231295 TBB5_HUMAN (1-429): 0: 704: 93.94		EFNA2_HUMAN (29-163): 8.77e-51: 169: 31.47
+	Hs
		457325 TBB5_HUMAN (1-429): 0: 704: 93.94		EFNA4_HUMAN (30-175): 5.99e-49: 164: 27.21
+	Hs
		231294 TBB4A_HUMAN (1-427): 0: 698: 93.21		EFNA2_HUMAN (29-163): 8.77e-51: 169: 31.47
+	Hs
		914256 TBB2A_HUMAN (1-430): 0: 699: 93.49		EFNA4_HUMAN (30-175): 5.99e-49: 164: 27.21