HitPredict

Interactor 1: EFNA2 (O43921)
Ephrin-A2 (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (HEK7 ligand) (HEK7-L)
Gene: EFNA2

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 450
+	Hs
		231295 EFNA2_HUMAN (1-213): 1e-90: 267: 100.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		231294 EFNA2_HUMAN (1-213): 1e-90: 267: 100.00		TBB4A_HUMAN (1-427): 0: 698: 93.21
+	Hs
		457228 EFNA1_HUMAN (18-210): 6.78e-78: 233: 40.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		635282 EFNA1_HUMAN (18-210): 6.78e-78: 233: 40.00		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		914197 EFNA3_HUMAN (30-189): 1.01e-61: 194: 46.71		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		914254 EFNA4_HUMAN (11-194): 1.01e-61: 192: 42.16		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		1108550 EFNB3_HUMAN (37-206): 9.1e-57: 184: 29.24		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		457324 EFNA3_HUMAN (30-189): 1.01e-61: 194: 46.71		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		914189 EFNA3_HUMAN (30-189): 1.01e-61: 194: 46.71		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		914214 EFNA3_HUMAN (30-189): 1.01e-61: 194: 46.71		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		457325 EFNA4_HUMAN (11-194): 1.01e-61: 192: 42.16		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		914256 EFNA4_HUMAN (11-194): 1.01e-61: 192: 42.16		TBB2A_HUMAN (1-430): 0: 699: 93.49
+	Hs
		1153466 EFNB3_HUMAN (37-206): 9.1e-57: 184: 29.24		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		457463 EFNB3_HUMAN (37-206): 9.1e-57: 184: 29.24		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		997356 EFNB3_HUMAN (37-206): 9.1e-57: 184: 29.24		TBB4B_HUMAN (1-427): 0: 703: 93.91