HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949739
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1893
+	Hs
		1110043 HDAC1_HUMAN (1-482): 0: 668: 100.00		CP250_HUMAN (54-1882): 1.97e-64: 245: 10.46
+	Hs
		552802 HDAC1_HUMAN (1-482): 0: 668: 100.00		TPR_HUMAN (1-1186): 2.69e-40: 166: 10.03
+	Hs
		1109726 HDAC1_HUMAN (1-482): 0: 668: 100.00		GOGB1_HUMAN (504-1878): 7.55e-40: 165: 10.75
+	Hs
		1105644 HDAC2_HUMAN (1-478): 0: 666: 85.92		GOGA4_HUMAN (8-888): 3.75e-30: 133: 12.15
+	Hs
		1109803 HDAC1_HUMAN (1-482): 0: 668: 100.00		MRCKA_HUMAN (51-491): 7.83e-24: 112: 14.26
+	Hs
		1110177 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (1184-1882): 2.68e-23: 110: 11.25
+	Hs
		1109744 HDAC1_HUMAN (1-482): 0: 668: 100.00		PLEC_HUMAN (564-1848): 4e-19: 97.3: 10.45
+	Hs
		563054 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (1209-1874): 2.22e-18: 94.6: 10.21
+	Hs
		772785 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (1199-1876): 4.9e-18: 93.4: 9.83
+	Hs
		772937 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (1199-1876): 4.9e-18: 93.4: 9.83
+	Hs
		556922 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (1239-1870): 3.92e-15: 84.2: 11.23
+	Hs
		1134665 HDAC2_HUMAN (1-478): 0: 666: 85.92		NUMA1_HUMAN (906-1615): 1.47e-14: 82.2: 10.88
+	Hs
		1110225 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (884-1666): 1.09e-12: 76.1: 12.76
+	Hs
		556850 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (1311-1852): 1.65e-12: 75.3: 11.91
+	Hs
		773240 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (1373-1866): 4.77e-13: 77.2: 12.97
+	Hs
		157335 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (160-734): 3.37e-11: 71: 16.67
+	Hs
		157696 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (160-734): 3.37e-11: 71: 16.67
+	Mm
		1240064 HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94		MYOME_MOUSE (28-1161): 1.48e-19: 98.4: 10.64
+	Mm
		1223386 HDAC6_MOUSE (11-325): 4.37e-103: 334: 25.69		MYH10_MOUSE (923-1877): 4.89e-33: 142: 10.83
+	Hs
		587833 HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78		DESP_HUMAN (35-576): 3.63e-27: 123: 16.16