Interactor 1: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Interactor 2: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 35271311, 32707033, 28514442, 32296183, 33961781, 20668654, unassigned1304, 29426014, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, cosedimentation in solution, validated two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~CaMKII_AD, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004683 - calcium/calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 12 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 558
Hs

1 499
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Dm
+ Hs
+ Hs
+ At
+ Gm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025