HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ANR39 (Q53RE8)
Ankyrin repeat domain-containing protein 39
Gene: ANKRD39

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.80	0.827

Property	Details
Experiments	33961781, 28514442, 35563538, 21145461, 34591642
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Cullin
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 183
+	Hs
		295498 CUL3_HUMAN (1-768): 0: 943: 100.00		PSD10_HUMAN (8-183): 2.86e-53: 170: 25.84
+	Hs
		1091393 CUL3_HUMAN (1-768): 0: 943: 100.00		ANK3_HUMAN (2-149): 3.89e-46: 163: 23.49
+	Hs
		920438 CUL3_HUMAN (1-768): 0: 943: 100.00		DAPK1_HUMAN (4-181): 1.61e-45: 161: 24.18
+	Hs
		1114326 CUL3_HUMAN (1-768): 0: 943: 100.00		EHMT1_HUMAN (3-143): 4.6e-41: 148: 19.58
+	Hs
		1113541 CUL3_HUMAN (1-768): 0: 943: 100.00		ANS1B_HUMAN (35-183): 8.63e-40: 145: 24.86
+	Hs
		592933 CUL3_HUMAN (1-768): 0: 943: 100.00		ANK1_HUMAN (23-176): 1.83e-39: 144: 24.03
+	Hs
		1114018 CUL3_HUMAN (1-768): 0: 943: 100.00		EHMT2_HUMAN (5-103): 3.33e-23: 97.7: 19.19
+	Hs
		1114046 CUL3_HUMAN (1-768): 0: 943: 100.00		ANR27_HUMAN (3-114): 3.53e-22: 94.7: 19.83
+	Hs
		1113629 CUL3_HUMAN (1-768): 0: 943: 100.00		ANKH1_HUMAN (88-183): 4.38e-21: 91.6: 27.27
+	Hs
		1114236 CUL3_HUMAN (1-768): 0: 943: 100.00		TANC1_HUMAN (43-182): 3.61e-20: 88.9: 20.21
+	Hs
		1091394 CUL4A_HUMAN (10-768): 0: 801: 38.32		ANK3_HUMAN (2-149): 3.89e-46: 163: 23.49
+	Hs
		1115234 CUL4B_HUMAN (5-768): 0: 796: 36.77		ANR39_HUMAN (1-183): 1.96e-51: 164: 100.00
+	Hs
		1115108 CUL4A_HUMAN (10-768): 0: 801: 38.32		RAI14_HUMAN (86-180): 1.14e-15: 75.8: 22.92
+	Hs
		1112526 CUL1_HUMAN (18-768): 0: 709: 30.57		ANR39_HUMAN (1-183): 1.96e-51: 164: 100.00
+	Hs
		1112865 CUL2_HUMAN (30-768): 0: 673: 26.17		ANR39_HUMAN (1-183): 1.96e-51: 164: 100.00
+	Hs
		943938 CUL1_HUMAN (18-768): 0: 709: 30.57		RIPK4_HUMAN (33-175): 1.13e-23: 99.1: 23.78
+	Hs
		1112713 CUL1_HUMAN (18-768): 0: 709: 30.57		Q9H4D1_HUMAN (33-175): 1.83e-23: 98.3: 23.78
+	Hs
		1371859 CUL5_HUMAN (25-768): 0: 597: 23.77		TNKS2_HUMAN (21-101): 5.03e-19: 85.6: 24.69