HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LRAD3 (Q86YD5)
Low-density lipoprotein receptor class A domain-containing protein 3 (LDLR class A domain-containing protein 3)
Gene: LDLRAD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 345
+	Hs
		1114511 CUL3_HUMAN (1-768): 0: 943: 100.00		TEN3_HUMAN (5-250): 5.31e-45: 166: 13.46
+	Hs
		376500 CUL3_HUMAN (1-768): 0: 943: 100.00		LDLR_HUMAN (30-238): 2.5e-23: 102: 18.41
+	Hs
		1113886 CUL3_HUMAN (1-768): 0: 943: 100.00		SORL_HUMAN (92-258): 3.93e-19: 91: 18.13
+	Hs
		1114494 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP1B_HUMAN (1-107): 1.87e-17: 86: 23.93
+	Hs
		1022513 CUL3_HUMAN (1-768): 0: 943: 100.00		VLDLR_HUMAN (109-266): 1.57e-17: 85.6: 13.04
+	Hs
		270553 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP4_HUMAN (109-256): 2.61e-17: 85.3: 14.38
+	Hs
		1113072 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP8_HUMAN (112-240): 1.08e-16: 83.3: 14.73
+	Hs
		1113520 CUL3_HUMAN (1-768): 0: 943: 100.00		TMPS7_HUMAN (103-246): 1.08e-16: 83.3: 18.75
+	Hs
		1022536 CUL3_HUMAN (1-768): 0: 943: 100.00		PGBM_HUMAN (5-90): 5.82e-14: 75.2: 20.83
+	Hs
		1022607 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP2_HUMAN (109-253): 1.78e-12: 70.6: 15.75
+	Hs
		1060870 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP1_HUMAN (5-145): 5.04e-11: 66.4: 21.82
+	Hs
		1115468 CUL4B_HUMAN (5-768): 0: 796: 36.77		LRP1B_HUMAN (1-107): 1.87e-17: 86: 23.93
+	Hs
		1115273 CUL4B_HUMAN (5-768): 0: 796: 36.77		TMPS7_HUMAN (103-246): 1.08e-16: 83.3: 18.75
+	Hs
		1022537 CUL4A_HUMAN (10-768): 0: 801: 38.32		PGBM_HUMAN (5-90): 5.82e-14: 75.2: 20.83
+	Hs
		1112633 CUL1_HUMAN (18-768): 0: 709: 30.57		SORL_HUMAN (92-258): 3.93e-19: 91: 18.13